PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

CTTN

Upstream kinases that phosphorylate CTTN

ADRBK1AKT1AURKBBMPR1BBMXCAMK2DCDK3CDK4CDK5CDK7
CDKL3CSKCSNK1A1CSNK2A2DDR2DYRK4FGFR1FGFR2FGFR4FGR
FYNGSK3BIGF1RJAK2LCKMAP2K4MAP3K7MAP4K5MAPK1MAPK3
METPAK1PAK4PDPK1PIM1PRKACAPRKCAPRKCHPRKCZPTK2B
RETRPS6KA2RPS6KB1SCYL2STK24STK38STK38LSTYK1SYKTGFBR2
TNK2TNNI3KWEE1YES1ZAP70

The sequence of CTTN

sites with predicted upstream kinases:
S113(GSK3B)
S117(PRKCA,PRKCH,RPS6KA2)
Y141(FGFR4,IGF1R,STYK1)
S150(BMPR1B,CSNK1A1,SCYL2)
Y154(PTK2B)
Y178(FGFR4,IGF1R,STYK1)
T182(BMPR1B,CSNK1A1,SCYL2)
Y215(FGFR4,IGF1R,STYK1)
S261(STYK1)
Y297(CSK)
T362(AKT1,CAMK2D,PAK4,PIM1,PRKACA,RPS6KB1)
T364(CDK3,CDK4,CDK5,CDK7,CDKL3,DYRK4,GSK3B,MAPK1,MAPK3)
S368(CDK3,CDK4,CDK5,CDK7,CDKL3,GSK3B,MAPK1,MAPK3)
T374(STK38,WEE1)
S380(CAMK2D,DYRK4,PAK4,PIM1,PRKACA,RPS6KB1,WEE1)
S381(CDK3,CDK4,CDK5,CDK7,CDKL3,MAPK1,MAPK3,STK38L)
Y384(DDR2,FGFR2,FYN,YES1)
S389(PRKCH)
Y409(CSK,FGFR1,PTK2B)
Y416(DYRK4,FGFR2)
Y433(BMX,CSK,DDR2,FGFR1,FGFR2,FGR,FYN,YES1,ZAP70)
Y449(LCK,STYK1)
Y501(FGFR1,WEE1)
Y508(MAP2K4,MET,STYK1)

Amino acids in red are phosphorylation sites determined by MS/MS
Mouseover sites for predicted upstream kinases
MWKASAGHAV SIAQDDAGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ 50
EHINIHKLRE NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV 100
GHEYQSKLSK HCSQVDSVRG FGGKFGVQMD RVDQSAVGFE YQGKTEKHAS 150
QKDYSSGFGG KYGVQADRVD KSAVGFDYQG KTEKHESQRD YSKGFGGKYG 200
IDKDKVDKSA VGFEYQGKTE KHESQKDYVK GFGGKFGVQT DRQDKCALGW 250
DHQEKLQLHE SQKDYSKGFG GKYGVQKDRM DKNASTFEDV TQVSSAYQKT 300
VPVEAVTSKT SNIRANFENL AKEKEQEDRR KAEAERAQRM AKERQEQEEA 350
RRKLEEQARA KTQTPPVSPA PQPTEERLPS SPVYEDAASF KAELSYRGPV 400
SGTEPEPVYS MEAADYREAS SQQGLAYATE AVYESAEAPG HYPAEDSTYD 450
EYENDLGITA VALYDYQAAG DDEISFDPDD IITNIEMIDD GWWRGVCKGR 500
YGLFPANYVE LRQ

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