PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

MAP2K1

Upstream kinases that phosphorylate MAP2K1

MAP3K8MAPK1PAK1RAF1

Substrates of MAP2K1

Mouseover proteins with red dots for specific sites predicted to be phosphorylated by MAP2K1.

GSK3BMAPK1MAPK3NEK3PRKCD

The phosphorylation motif of MAP2K1

click the image for details

The sequence of MAP2K1

sites with predicted upstream kinases:
S24(MAP3K8)
S231(MAPK1)
T286(MAPK1)
T292(MAPK1,RAF1)
S298(RAF1)
T386(MAPK1)

Amino acids in red are phosphorylation sites determined by MS/MS
Mouseover sites for predicted upstream kinases
MPKKKPTPIQ LNPAPDGSAV NGTSSAETNL EALQKKLEEL ELDEQQRKRL 50
EAFLTQKQKV GELKDDDFEK ISELGAGNGG VVFKVSHKPS GLVMARKLIH 100
LEIKPAIRNQ IIRELQVLHE CNSPYIVGFY GAFYSDGEIS ICMEHMDGGS 150
LDQVLKKAGR IPEQILGKVS IAVIKGLTYL REKHKIMHRD VKPSNILVNS 200
RGEIKLCDFG VSGQLIDSMA NSFVGTRSYM SPERLQGTHY SVQSDIWSMG 250
LSLVEMAVGR YPIPPPDAKE LELMFGCQVE GDAAETPPRP RTPGRPLSSY 300
GMDSRPPMAI FELLDYIVNE PPPKLPSGVF SLEFQDFVNK CLIKNPAERA 350
DLKQLMVHAF IKRSDAEEVD FAGWLCSTIG LNQPSTPTHA AGV 400

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