PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

MAPK1

Upstream kinases that phosphorylate MAPK1

ACVR1BBTKCAMK2DCSNK1DDCLK1DYRK1BFGFR4FGRHIPK1MAP2K1
MAP2K3MAPK14MAPK8MAPKAPK5RIPK3RPS6KA1RPS6KA5SCYL2SRPK2STK16
TBK1WNK1YES1

Substrates of MAPK1

Mouseover proteins with red dots for specific sites predicted to be phosphorylated by MAPK1.

APBB1BCL2L11CADCAPN2CASP9CDKN1BCEBPACLK3CSNK1G2CSRP3
CTTNDAPK1DDEFL1DUSP1DUSP16DUSP6EGFREIF2AK2ERFESPL1
FGRFOSGAB1GADD45AGRB10GSK3BHLCSIL16LCKLIFR
MAP2K1MAPKAPK2MAPKAPK5MBPMCL1MDM2MDM4MED1MED28MTA1
MYCNCOA1NFATC4NUP133OTUD7BPAK1PGRPHF17PITPNM1PLA2G4A
POLR2APPARGPPP1R13LPRKAR1ARAD23BRAD51RELARGS19RNH1RPS3
RPS6KA5RXRASH2B1SMAD1SMAD3SMC3SOS1SOX10SP1SREBF1
SREBF2SRXN1STAT5ASTK16THRBTOP2ATP53TSC2TSC22D3UBE2A
UBTFZBED1

The phosphorylation motif of MAPK1

click the image for details

The sequence of MAPK1

Amino acids in red are phosphorylation sites determined by MS/MS

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