PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

MAPKAPK5

Upstream kinases that phosphorylate MAPKAPK5

MAPK1MAPK11MAPK14MAPK9

Substrates of MAPKAPK5

Mouseover proteins with red dots for specific sites predicted to be phosphorylated by MAPKAPK5.

ASCC1BCL3CBLCHEK1CIAO1CLK1CSDC2CSDE1CSRP3DAXX
DDEF2EIF4A2EIF4BEIF4ENIF1ETF1ETS1EXOSC5GPBP1HCLS1IRF3
KLHL25MAPK1MAPK12MAPK8MBNL3MDFIMDM2NEUROD1NFATC4NPM1
POP7PPP1R13LPRKACAPRKACBPSMA6PSMC3RAD23BRETRUVBL1RUVBL2
S100A11SAFB2SARSSF3B4SFRS1SIP1SMAD4SMPXSND1SRXN1
SUMO4TBC1D22ATRIM24UBE2IUBE2NUHMK1ZYX

The phosphorylation motif of MAPKAPK5

click the image for details

The sequence of MAPKAPK5

sites with predicted upstream kinases:
T182(MAPK1,MAPK11,MAPK14,MAPK9)
T214(MAPK1)

Amino acids in red are phosphorylation sites determined by MS/MS
Mouseover sites for predicted upstream kinases
MSEESDMDKA IKETSILEEY SINWTQKLGA GISGPVRVCV KKSTQERFAL 50
KILLDRPKAR NEVRLHMMCA THPNIVQIIE VFANSVQFPH ESSPRARLLI 100
VMEMMEGGEL FHRISQHRHF TEKQASQVTK QIALALRHCH LLNIAHRDLK 150
PENLLFKDNS LDAPVKLCDF GFAKIDQGDL MTPQFTPYYV APQVLEAQRR 200
HQKEKSGIIP TSPTPYTYNK SCDLWSLGVI IYVMLCGYPP FYSKHHSRTI 250
PKDMRRKIMT GSFEFPEEEW SQISEMAKDV VRKLLKVKPE ERLTIEGVLD 300
HPWLNSTEAL DNVLPSAQLM MDKAVVAGIQ QAHAEQLANM RIQDLKVSLK 350
PLHSVNNPIL RKRKLLGTKP KDSVYIHDHE NGAEDSNVAL EKLRDVIAQC 400
ILPQAGENED EKLNEVMQEA WKYNRECKLL RDTLQSFSWN GRGFTDKVDR 450
LKLAEIVKQV IEEQTTSHES Q

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