PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

MYC

Upstream kinases that phosphorylate MYC

GSK3AGSK3BMAPK1

The sequence of MYC

sites with predicted upstream kinases:
T58(GSK3A,GSK3B,MAPK1)
S62(MAPK1)
S71(MAPK1)
S277(GSK3A,GSK3B)
S293(MAPK1)
S344(GSK3A,GSK3B)

Amino acids in red are phosphorylation sites determined by MS/MS
Mouseover sites for predicted upstream kinases
MPLNVSFTNR NYDLDYDSVQ PYFYCDEEEN FYQQQQQSEL QPPAPSEDIW 50
KKFELLPTPP LSPSRRSGLC SPSYVAVTPF SLRGDNDGGG GSFSTADQLE 100
MVTELLGGDM VNQSFICDPD DETFIKNIII QDCMWSGFSA AAKLVSEKLA 150
SYQAARKDSG SPNPARGHSV CSTSSLYLQD LSAAASECID PSVVFPYPLN 200
DSSSPKSCAS QDSSAFSPSS DSLLSSTESS PQGSPEPLVL HEETPPTTSS 250
DSEEEQEDEE EIDVVSVEKR QAPGKRSESG SPSAGGHSKP PHSPLVLKRC 300
HVSTHQHNYA APPSTRKDYP AAKRVKLDSV RVLRQISNNR KCTSPRSSDT 350
EENVKRRTHN VLERQRRNEL KRSFFALRDQ IPELENNEKA PKVVILKKAT 400
AYILSVQAEE QKLISEEDLL RKRREQLKHK LEQLRNSCA

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