PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

POLR2A

Upstream kinases that phosphorylate POLR2A

CDK9MAPK1MAPK3

The sequence of POLR2A

sites with predicted upstream kinases:
S1616(CDK9,MAPK1,MAPK3)
S1619(CDK9,MAPK1,MAPK3)
S1815(CDK9,MAPK1,MAPK3)
S1836(CDK9,MAPK1,MAPK3)
T1840(CDK9,MAPK1,MAPK3)
S1843(CDK9,MAPK1,MAPK3)
S1847(CDK9,MAPK1,MAPK3)
S1850(CDK9,MAPK1,MAPK3)
T1854(CDK9,MAPK1,MAPK3)
S1857(CDK9,MAPK1,MAPK3)
S1861(CDK9,MAPK1,MAPK3)
S1864(CDK9,MAPK1,MAPK3)
S1868(CDK9,MAPK1,MAPK3)
S1875(CDK9,MAPK1,MAPK3)
S1878(CDK9,MAPK1,MAPK3)
S1882(CDK9,MAPK1,MAPK3)
T1885(CDK9,MAPK1,MAPK3)
S1889(CDK9,MAPK1,MAPK3)
S1892(CDK9,MAPK1,MAPK3)
S1896(CDK9,MAPK1,MAPK3)
S1899(CDK9,MAPK1,MAPK3)
T1903(CDK9,MAPK1,MAPK3)
S1906(CDK9,MAPK1,MAPK3)
S1913(CDK9,MAPK1,MAPK3)
S1917(CDK9,MAPK1,MAPK3)
S1920(CDK9,MAPK1,MAPK3)
S1931(CDK9,MAPK1,MAPK3)
S1934(CDK9,MAPK1,MAPK3)
S1962(CDK9)

Amino acids in red are phosphorylation sites determined by MS/MS
Mouseover sites for predicted upstream kinases
MHGGGPPSGD SACPLRTIKR VQFGVLSPDE LKRMSVTEGG IKYPETTEGG 50
RPKLGGLMDP RQGVIERTGR CQTCAGNMTE CPGHFGHIEL AKPVFHVGFL 100
VKTMKVLRCV CFFCSKLLVD SNNPKIKDIL AKSKGQPKKR LTHVYDLCKG 150
KNICEGGEEM DNKFGVEQPE GDEDLTKEKG HGGCGRYQPR IRRSGLELYA 200
EWKHVNEDSQ EKKILLSPER VHEIFKRISD EECFVLGMEP RYARPEWMIV 250
TVLPVPPLSV RPAVVMQGSA RNQDDLTHKL ADIVKINNQL RRNEQNGAAA 300
HVIAEDVKLL QFHVATMVDN ELPGLPRAMQ KSGRPLKSLK QRLKGKEGRV 350
RGNLMGKRVD FSARTVITPD PNLSIDQVGV PRSIAANMTF AEIVTPFNID 400
RLQELVRRGN SQYPGAKYII RDNGDRIDLR FHPKPSDLHL QTGYKVERHM 450
CDGDIVIFNR QPTLHKMSMM GHRVRILPWS TFRLNLSVTT PYNADFDGDE 500
MNLHLPQSLE TRAEIQELAM VPRMIVTPQS NRPVMGIVQD TLTAVRKFTK 550
RDVFLERGEV MNLLMFLSTW DGKVPQPAIL KPRPLWTGKQ IFSLIIPGHI 600
NCIRTHSTHP DDEDSGPYKH ISPGDTKVVV ENGELIMGIL CKKSLGTSAG 650
SLVHISYLEM GHDITRLFYS NIQTVINNWL LIEGHTIGIG DSIADSKTYQ 700
DIQNTIKKAK QDVIEVIEKA HNNELEPTPG NTLRQTFENQ VNRILNDARD 750
KTGSSAQKSL SEYNNFKSMV VSGAKGSKIN ISQVIAVVGQ QNVEGKRIPF 800
GFKHRTLPHF IKDDYGPESR GFVENSYLAG LTPTEFFFHA MGGREGLIDT 850
AVKTAETGYI QRRLIKSMES VMVKYDATVR NSINQVVQLR YGEDGLAGES 900
VEFQNLATLK PSNKAFEKKF RFDYTNERAL RRTLQEDLVK DVLSNAHIQN 950
ELEREFERMR EDREVLRVIF PTGDSKVVLP CNLLRMIWNA QKIFHINPRL 1000
PSDLHPIKVV EGVKELSKKL VIVNGDDPLS RQAQENATLL FNIHLRSTLC 1050
SRRMAEEFRL SGEAFDWLLG EIESKFNQAI AHPGEMVGAL AAQSLGEPAT 1100
QMTLNTFHYA GVSAKNVTLG VPRLKELINI SKKPKTPSLT VFLLGQSARD 1150
AERAKDILCR LEHTTLRKVT ANTAIYYDPN PQSTVVAEDQ EWVNVYYEMP 1200
DFDVARISPW LLRVELDRKH MTDRKLTMEQ IAEKINAGFG DDLNCIFNDD 1250
NAEKLVLRIR IMNSDENKMQ EEEEVVDKMD DDVFLRCIES NMLTDMTLQG 1300
IEQISKVYMH LPQTDNKKKI IITEDGEFKA LQEWILETDG VSLMRVLSEK 1350
DVDPVRTTSN DIVEIFTVLG IEAVRKALER ELYHVISFDG SYVNYRHLAL 1400
LCDTMTCRGH LMAITRHGVN RQDTGPLMKC SFEETVDVLM EAAAHGESDP 1450
MKGVSENIML GQLAPAGTGC FDLLLDAEKC KYGMEIPTNI PGLGAAGPTG 1500
MFFGSAPSPM GGISPAMTPW NQGATPAYGA WSPSVGSGMT PGAAGFSPSA 1550
ASDASGFSPG YSPAWSPTPG SPGSPGPSSP YIPSPGGAMS PSYSPTSPAY 1600
EPRSPGGYTP QSPSYSPTSP SYSPTSPSYS PTSPNYSPTS PSYSPTSPSY 1650
SPTSPSYSPT SPSYSPTSPS YSPTSPSYSP TSPSYSPTSP SYSPTSPSYS 1700
PTSPSYSPTS PSYSPTSPSY SPTSPSYSPT SPSYSPTSPS YSPTSPNYSP 1750
TSPNYTPTSP SYSPTSPSYS PTSPNYTPTS PNYSPTSPSY SPTSPSYSPT 1800
SPSYSPSSPR YTPQSPTYTP SSPSYSPSSP SYSPTSPKYT PTSPSYSPSS 1850
PEYTPTSPKY SPTSPKYSPT SPKYSPTSPT YSPTTPKYSP TSPTYSPTSP 1900
VYTPTSPKYS PTSPTYSPTS PKYSPTSPTY SPTSPKGSTY SPTSPGYSPT 1950
SPTYSLTSPA ISPDDSDEEN

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