PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

SOX10

Upstream kinases that phosphorylate SOX10

AURKBCAMK4CDK5CDK7CHEK2CSNK1ECSNK2A2DDR1FGFR4FYN
HIPK4MAPK1MAPK9NEK4NRBP2PAK1PIM1PRKCIPXKRAF1
RAGESNRKSRPK2TGFBR2

The sequence of SOX10

sites with predicted upstream kinases:
S24(CDK5,CDK7,CHEK2,MAPK1,MAPK9,NEK4,NRBP2,PIM1,RAF1)
S45(AURKB,CDK7,MAPK1,MAPK9,PAK1,RAGE)

Amino acids in red are phosphorylation sites determined by MS/MS
Mouseover sites for predicted upstream kinases
MAEEQDLSEV ELSPVGSEEP RCLSPGSAPS LGPDGGGGGS GLRASPGPGE 50
LGKVKKEQQD GEADDDKFPV CIREAVSQVL SGYDWTLVPM PVRVNGASKS 100
KPHVKRPMNA FMVWAQAARR KLADQYPHLH NAELSKTLGK LWRLLNESDK 150
RPFIEEAERL RMQHKKDHPD YKYQPRRRKN GKAAQGEAEC PGGEAEQGGT 200
AAIQAHYKSA HLDHRHPGEG SPMSDGNPEH PSGQSHGPPT PPTTPKTELQ 250
SGKADPKRDG RSMGEGGKPH IDFGNVDIGE ISHEVMSNME TFDVAELDQY 300
LPPNGHPGHV SSYSAAGYGL GSALAVASGH SAWISKPPGV ALPTVSPPGV 350
DAKAQVKTET AGPQGPPHYT DQPSTSQIAY TSLSLPHYGS AFPSISRPQF 400
DYSDHQPSGP YYGHSGQASG LYSAFSYMGP SQRPLYTAIS DPSPSGPQSH 450
SPTHWEQPVY TTLSRP

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