PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

Substrates of TBK1

Mouseover proteins with red dots for specific sites predicted to be phosphorylated by TBK1.

ASCC1C21orf66CBLCERKCRY1CSDC2DDX25DNMT3ADOK1GNA12
HADHBHDAC3HLCSHSPB1IRF3IRF5MAPK1MDM2MTA1NEUROD1
PPP1R13LPSPC1RCHY1RELARIPK3RPA2RUVBL2SMPXSRXN1STUB1
SUMO4TMSL3VHLXPO1YWHAEYWHAHZAP70

The phosphorylation motif of TBK1

click the image for details

The sequence of TBK1

Amino acids in red are phosphorylation sites determined by MS/MS
MQSTSNHLWL LSDILGQGAT ANVFRGRHKK TGDLFAIKVF NNISFLRPVD 50
VQMREFEVLK KLNHKNIVKL FAIEEETTTR HKVLIMEFCP CGSLYTVLEE 100
PSNAYGLPES EFLIVLRDVV GGMNHLRENG IVHRDIKPGN IMRVIGEDGQ 150
SVYKLTDFGA ARELEDDEQF VSLYGTEEYL HPDMYERAVL RKDHQKKYGA 200
TVDLWSIGVT FYHAATGSLP FRPFEGPRRN KEVMYKIITG KPSGAISGVQ 250
KAENGPIDWS GDMPVSCSLS RGLQVLLTPV LANILEADQE KCWGFDQFFA 300
ETSDILHRMV IHVFSLQQMT AHKIYIHSYN TATIFHELVY KQTKIISSNQ 350
ELIYEGRRLV LEPGRLAQHF PKTTEENPIF VVSREPLNTI GLIYEKISLP 400
KVHPRYDLDG DASMAKAITG VVCYACRIAS TLLLYQELMR KGIRWLIELI 450
KDDYNETVHK KTEVVITLDF CIRNIEKTVK VYEKLMKINL EAAELGEISD 500
IHTKLLRLSS SQGTIETSLQ DIDSRLSPGG SLADAWAHQE GTHPKDRNVE 550
KLQVLLNCMT EIYYQFKKDK AERRLAYNEE QIHKFDKQKL YYHATKAMTH 600
FTDECVKKYE AFLNKSEEWI RKMLHLRKQL LSLTNQCFDI EEEVSKYQEY 650
TNELQETLPQ KMFTASSGIK HTMTPIYPSS NTLVEMTLGM KKLKEEMEGV 700
VKELAENNHI LERFGSLTMD GGLRNVDCL

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