PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

TP53

Upstream kinases that phosphorylate TP53

ADRBK1CDK7CHEK2EIF2AK2MAPK1PAK4RPS6KA3

The sequence of TP53

sites with predicted upstream kinases:
S33(CDK7,MAPK1)
S37(CHEK2)
S46(ADRBK1)
T81(CDK7,MAPK1)
S315(CDK7)

Amino acids in red are phosphorylation sites determined by MS/MS
Mouseover sites for predicted upstream kinases
MEEPQSDPSV EPPLSQETFS DLWKLLPENN VLSPLPSQAM DDLMLSPDDI 50
EQWFTEDPGP DEAPRMPEAA PRVAPAPAAP TPAAPAPAPS WPLSSSVPSQ 100
KTYQGSYGFR LGFLHSGTAK SVTCTYSPAL NKMFCQLAKT CPVQLWVDST 150
PPPGTRVRAM AIYKQSQHMT EVVRRCPHHE RCSDSDGLAP PQHLIRVEGN 200
LRVEYLDDRN TFRHSVVVPY EPPEVGSDCT TIHYNYMCNS SCMGGMNRRP 250
ILTIITLEDS SGNLLGRNSF EVRVCACAGR DRRTEEENLR KKGEPHHELP 300
PGSTKRALPN NTSSSPQPKK KPLDGEYFTL QIRGRERFEM FRELNEALEL 350
KDAQAGKEPG GSRAHSSHLK SKKGQSTSRH KKLMFKTEGP DSD 400

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