PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

WNK1

Upstream kinases that phosphorylate WNK1

PAK4

Substrates of WNK1

Mouseover proteins with red dots for specific sites predicted to be phosphorylated by WNK1.

ANKS1ADDEFL1HLCSMAPK1NEUROD1NFATC4OXSR1PPP2R5DPRKCDRPS6KA2
STK39SUFUVHLZYX

The phosphorylation motif of WNK1

click the image for details

The sequence of WNK1

sites with predicted upstream kinases:
T60(PAK4)
S167(PAK4)
S185(PAK4)

Amino acids in red are phosphorylation sites determined by MS/MS
Mouseover sites for predicted upstream kinases
MSGGAAEKQS STPGSLFLSP PAPAPKNGSS SDSSVGEKLG AAAADAVTGR 50
TEEYRRRRHT MDKDSRGAAA TTTTTEHRFF RRSVICDSNA TALELPGLPL 100
SLPQPSIPAA VPQSAPPEPH REETVTATAT SQVAQQPPAA AAPGEQAVAG 150
PAPSTVPSST SKDRPVSQPS LVGSKEEPPP ARSGSGGGSA KEPQEERSQQ 200
QDDIEELETK AVGMSNDGRF LKFDIEIGRG SFKTVYKGLD TETTVEVAWC 250
ELQDRKLTKS ERQRFKEEAE MLKGLQHPNI VRFYDSWEST VKGKKCIVLV 300
TELMTSGTLK TYLKRFKVMK IKVLRSWCRQ ILKGLQFLHT RTPPIIHRDL 350
KCDNIFITGP TGSVKIGDLG LATLKRASFA KSVIGMFQVY LGA 400

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