PhosphoNetworks

- A database for experimentally determined kinase-substrate relationships

YES1

Upstream kinases that phosphorylate YES1

CSK

Substrates of YES1

Mouseover proteins with red dots for specific sites predicted to be phosphorylated by YES1.

CBLCTTNDDEFL1ENO1FYNG3BP1GSNHLCSHSPA8MAPK1
MBNL3MSNNPM1NUDT4PKM2PRKAR1ARAP1ARELAS100A11SMAD4
SRXN1TBC1D22ATRIM29TXNUBBUBTD2YWHAHYWHAZ

The phosphorylation motif of YES1

click the image for details

The sequence of YES1

sites with predicted upstream kinases:
Y345(CSK)
Y537(CSK)

Amino acids in red are phosphorylation sites determined by MS/MS
Mouseover sites for predicted upstream kinases
MGCIKSKENK SPAIKYRPEN TPEPVSTSVS HYGAEPTTVS PCPSSSAKGT 50
AVNFSSLSMT PFGGSSGVTP FGGASSSFSV VPSSYPAGLT GGVTIFVALY 100
DYEARTTEDL SFKKGERFQI INNTEGDWWE ARSIATGKNG YIPSNYVAPA 150
DSIQAEEWYF GKMGRKDAER LLLNPGNQRG IFLVRESETT KGAYSLSIRD 200
WDEIRGDNVK HYKIRKLDNG GYYITTRAQF DTLQKLVKHY TEHADGLCHK 250
LTTVCPTVKP QTQGLAKDAW EIPRESLRLE VKLGQGCFGE VWMGTWNGTT 300
KVAIKTLKPG TMMPEAFLQE AQIMKKLRHD KLVPLYAVVS EEPIYIVTEF 350
MSKGSLLDFL KEGDGKYLKL PQLVDMAAQI ADGMAYIERM NYIHRDLRAA 400
NILVGENLVC KIADFGLARL IEDNEYTARQ GAKFPIKWTA PEAALYGRFT 450
IKSDVWSFGI LQTELVTKGR VPYPGMVNRE VLEQVERGYR MPCPQGCPES 500
LHELMNLCWK KDPDERPTFE YIQSFLEDYF TATEPQYQPG ENL 550

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